Best peptides for muscle growth

Research information only, not medical advice. The peptides associated with muscle growth are mostly growth-hormone secretagogues — they raise growth hormone and IGF-1. Ranked below by human evidence. Note how thin the human data is for most: the effect on lean mass in people is far less established than the marketing suggests.

# Peptide Searches/mo Human Preclinical Top grade
1 Tesamorelin 58,000 28% 15% Human RCT
2 Ibutamoren 17,000 18% 32% Human RCT
3 Ipamorelin high demand, low evidence 30,000 9% 36% Preclinical
4 CJC-1295 9,500 4% 35% Preclinical
5 Sermorelin high demand, low evidence 117,000 3% 20% Human trial

Ranked by the share of indexed studies that is human, Tesamorelin leads the peptides studied for muscle growth. For the full picture across every peptide, see the Peptide Evidence Index, or open a molecule to read its trials and regulatory status. How each level is assigned is on our methodology page.

Frequently asked questions

What is the best peptide for muscle growth?
Ranked by human evidence, Tesamorelin has the strongest human backing of the peptides studied for muscle growth (28% of its indexed studies are human). Most others in this list rest mainly on animal or in-vitro work.
Do peptides work for muscle growth?
For most of these peptides the human evidence is limited — the table shows the human-evidence share for each. This is research information, not medical advice.

Search demand captured · evidence corpus refreshed weekly · sourced to primary documents